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There is enormous exuberance about starting GLP-1 drugs, but not nearly enough attention to what happens when people stop, senior study author Ziyad Al-Aly, MD, a Washington University School of Medicine clinical epidemiologist and chief of the Research and Development Service at the VA Saint Louis Health Care System, said in a press release

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For instance, the GLP-1R agonist semaglutide promotes tumor cell proliferation in neuroendocrine cancer (40), whereas a meta-analysis encompassing eight original studies revealed that GLP-1R agonists may confer protective effects against liver cancer (24,41)

doi: 10.1016/j.avsg.2020.10.022 64 ArmstrongDGBoultonAJMBusSA